You are : Issues Cancer > Chemicals
   

ISSUES

- Climate Change &
  Global Warming:
  Action!

- Cancer

 

Table 1.
Proportion of Chemicals Evaluated as Carcinogenic

 

Proportion

Percent

 

Chemicals tested in both rats and micea

350/590

(59%)

 

Naturally-occurring chemicals

79/139

(57%)

 

Synthetic chemicals

271/451

(60%)

     

Chemicals tested in rats and/or micea

 

 

 

Chemicals in Carcinogenic Potency Database

702/1348

(52%)

 

Natural pesticides

37/71

(52%)

 

Mold toxins

14/23

(61%)

 

Chemicals in roasted coffee

21/30

(70%)

     

Innes negative chemicals retesteda,b

17/34

(50%)

Physician's Desk Reference (PDR):

 

 

Drugs with reported cancer testsc

117/241

(49%)

FDA database of drug submissionsd

125/282

(44%)

GreenBalance note: How to read this table?
The Proportion column gives the number of chemicals that was found to cause cancer in high animal dose tests, followed by the number of chemicals tested.
The Percent column gives the percentage of chemicals that was found to cause cancer in high animal dose tests.

a From the Carcinogenic Potency Database [1;3].
b The 1969 study by Innes et al [90] is frequently cited as evidence that the proportion of carcinogens is low, as only 9% of 119 chemicals tested (primarily pesticides) were positive. However, these tests, which were only in mice with few animals per group, lacked the power of modern tests. Of the 34 Innes negative chemicals that have been retested using modern protocols: 16 were positive.
c Davies and Monro [91].
d Contrera et al. [92]. 140 drugs are in both the FDA and PDR databases.

Article reprinted from Mutation Research Frontiers, 7 September 1999
Source: http://ec.europa.eu/environment/archives/ppps/pdf/ma_reding_annex2.pdf

 back
Revised April 23, 2015
top