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Table 2.
Carcinogenicity of natural plant pesticides tested in rodentsa

Carcinogens: N=37


acetaldehyde methylformylhydrazone, allyl isothiocyanate, arecoline.HCl, benzaldehyde, benzyl acetate, caffeic acid, capsaicin, catechol, clivorine, coumarin, crotonaldehyde, 3,4-dihydrocoumarin, estragole, ethyl acrylate, N2-g-glutamyl-p-hydrazinobenzoic acid, hexanal methylformylhydrazine, p-hydrazinobenzoic acid.HCl, hydroquinone, 1-hydroxyanthraquinone, lasio­carpine, d-limonene, 3-methoxycatechol, 8-methoxypsoralen, N-methyl-N-formylhydrazine, a-methylbenzyl alcohol, 3-methylbutanal methylformylhydrazone, 4-methylcatechol, methylhydrazine, monocro­taline, pentanal methylformylhydrazone, petasitenine, quercetin, reserpine, safrole, senkirkine, sesamol, symphytine

Atropine, benzyl alcohol, benzyl isothiocyanate, benzyl thiocyanate, biphenyl, d-carvone, codeine, deserpidine, disodium glycyrrhizinate, ephedrine sulphate, epigallocatechin eucalyptol, eugenol, gallic acid, geranyl acetate, b-N-[g-l(+)-glutamyl]-4-hydroxy-methylphenylhydrazine, glycyrrhetinic acid, p-hydrazinobenzoic acid, isosafrole, kaempferol, d-menthol, nicotine, norharman, phenethyl isothiocyanate, pilocarpine, piperidine, protocatechuic acid, rotenone, rutin sulfate, sodium benzoate, tannic acid, 1-trans-d9-tetrahydrocannabinol, turmeric oleoresin, vinblastine

These rodent carcinogens occur in: absinthe, allspice, anise, apple, apricot, banana, basil, beet, broccoli, Brussels sprouts, cabbage, cantaloupe, caraway, cardamom, carrot, cauliflower, celery, cherries, chili pepper, chocolate, cinnamon, cloves, coffee, collard greens, comfrey herb tea, corn, coriander, currants, dill, eggplant, endive, fennel, garlic, grapefruit, grapes, guava, honey, honeydew melon, horseradish, kale, lemon, lentils, lettuce, licorice, lime, mace, mango, marjoram, mint, mushrooms, mustard, nutmeg, onion, orange, paprika, parsley, parsnip, peach, pear, peas, black pepper, pineapple, plum, potato, radish, raspberries, rhubarb, rosemary, rutabaga, sage, savory, sesame seeds, soybean, star anise, tarragon, tea, thyme, tomato, turmeric, and turnip.

a Fungal toxins are not included. From the Carcinogenic Potency Database [1;3].

Article reprinted from Mutation Research Frontiers, 7 September 1999

Revised April 23, 2015