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Table 3.
Carcinogenicity in rodents of natural chemicals in roasted coffeea

Positive: N = 21

Not positive: N = 8


Yet to test:

acetaldehyde, benzaldehyde, benzene, benzofuran, benzo(a)pyrene, caffeic acid, catechol, 1,2,5,6-dibenzanthracene, ethanol, ethylbenzene, formaldehyde, furan, furfural, hydrogen peroxide, hydroquinone, isoprene, limonene, 4-methylcatechol, styrene, toluene, xylene

acrolein, biphenyl, choline, eugenol, nicotinamide, nicotinic acid, phenol, piperidine


~ 1000 chemicals

GreenBalance note: How to understand this table?
About 1000 natural substances (= natural chemicals) have been identified in roasted coffee.
30 of them have been tested in laboratory rodents (rats, mice...) using high dose tests.
Out of these, 21 were found to cause cancer to the rodents.

a From the Carcinogenic Potency Database [1;3].

Article reprinted from Mutation Research Frontiers, 7 September 1999


Revised April 23, 2015